Rewriting the Blueprint
Gene editing for improved agriculture, healthcare, and beyond.
Sources & References
Header Icon:
"Home" Content:
"Home" Media Elements (images, videos, infographics):
HME.1: https://www.littlebabylife.com/wp-content/uploads/2017/11/wake-sleeping-baby.jpg
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HME.4: https://www.sciencealert.com/images/articles/processed/baby-hiv-hand_600.jpg
HME.5: https://brocku.ca/brock-news/wp-content/uploads/2018/03/Newborn-baby-1600x1164.jpg?x68208
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HME.16: https://www.amazopedia.com/wp-content/uploads/2019/10/shutterstock_480784465-1366x800@2x.jpg
"Background" Content:
BC.1: https://www.synthego.com/learn/genome-engineering-history
BC.2: https://di.uq.edu.au/community-and-alumni/sparq-ed/sparq-ed-services/dna-ligation
BC.3: https://www.thoughtco.com/microinjection-375568
BC.4: https://www.xxpresspcr.com/all-news/applications-in-pcr-pcr-in-genetic-and-genome-engineering/
"Background" Media Elements (images, videos, infographics):
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BME.9: https://www.jcvi.org/sites/default/files/assets/bio/smith-hamilton.jpg
BME.10: https://en.lifeder.com/wp-content/uploads/2019/01/HindIII-restriction-enzyme.png
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BME.15: https://www.biology.iupui.edu/biocourses/Biol540/images/3humulin.jpg
BME.16: https://melanomanewstoday.com/wp-content/uploads/2014/07/Genentech.jpg
BME.17: https://www.bosterbio.com/media/images/MB_PCR_components.png
BME.18: https://www.youtube.com/watch?v=iGmq1O6mIy0
BME.20: https://geneticliteracyproject.org/wp-content/uploads/2018/05/genes-5-30-18.jpg
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BME.24: https://www.pmlive.com/__data/assets/image/0017/474002/Novartis-Glivec-imatinib-leukaemia.jpg
BME.26: https://www.fishtanksetups.com/wp-content/uploads/2019/10/how-are-glofish-made.jpg
BME.28: https://cdn.hswstatic.com/gif/stem-cell-670.jpg
BME.29: https://www.oxinst.com/learning/uploads/inline-images/gene-editing01b-20190312144705.jpg
BME.31: https://i0.wp.com/www.dailycal.org/assets/uploads/2020/01/doudna1_doudnalab_courtesy-900x580.jpg
BME.35: https://www.labiotech.eu/wp-content/uploads/2019/11/crispr-therapeutics-vertex-beta-thalassemia.jpg
"Applications" Content:
AC.1: https://www.labiotech.eu/tops/crispr-technology-cure-disease/
AC.2: https://www.drugtargetreview.com/news/29911/crispr-cas9-huntingtons-disease/
AC.3: http://sitn.hms.harvard.edu/flash/2019/crispr-scanning-towards-new-drugs-drug-discovery
-is-difficult-but-crispr-might-be-able-to-help/
AC.4: https://www.labiotech.eu/features/crispr-cas9-drug-discovery/
AC.5: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5002234/pdf/nihms-792785.pdf
AC.6: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5012545/pdf/mtna201543a.pdf
AC.7: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3547402/pdf/nihms429552.pdf
AC.8: https://www.npr.org/sections/health-shots/2019/08/22/746321083/scientists-attempt-
Controversial-experiment-to-edit-dna-in-human-sperm-using-cri
AC.9: https://www.bbvaopenmind.com/en/articles/the-biological-breakthrough-of-crispr-
AC.10: https://www.technologynetworks.com/genomics/news/crispr-and-infertility-mutation-
Disrupts-embryo-implantation-315144
AC.11: https://www.microsort.com/requirements/
AC.12: https://www.nature.com/articles/d41586-019-02087-5
AC.13: https://singularityhub.com/2017/02/26/would-you-want-a-dog-that-was-
genetically-engineered-to-be-healthier/
AC.14: https://www.nature.com/scitable/topicpage/genetically-modified-organisms-gmos-
AC.15: http://sitn.hms.harvard.edu/flash/2015/good-as-gold-can-golden-rice-and-other-biofortified
AC.16: http://www.goldenrice.org/Content2-How/how1_sci.php
AC.17: https://entomology.ca.uky.edu/ef130
AC.18: https://blogs.scientificamerican.com/guest-blog/allergy-free-peanuts-not-so-fast/
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"Applications" Media Elements (images, videos, infographics):
AME.1: https://static.wixstatic.com/media/5a7fdb_df621506eab64a67bd1f1f7e34692b94~mv2.jpg
AME.2: https://static.wixstatic.com/media/5a7fdb_563472bef8c846749837c84e9add2d54~mv2.jpg
AME.4: https://www.cmm.com.au/img/uploads/blog_posts/20160817122252.jpg
AME.5: https://media.pharmoutsourcing.com/m/30/article/352619.jpg
AME.6: https://live.staticflickr.com/4917/46291373491_704576099e_b.jpg
AME.7: https://static.wixstatic.com/media/5a7fdb_330121ab7a3b46ebbca18088c8ce96d0~mv2.jpg
AME.9: https://www.nature.com/articles/d41586-019-02087-5
AME.10: https://static.wixstatic.com/media/5a7fdb_e744190bdca949c6847f6fb0c31ac201~mv2.jpg
AME.11: https://img.freepik.com/free-photo/experimental-mice-science_159160-272.jpg?size=626&ext=jpg
AME.12: https://www.animalaid.org.uk/wp-content/uploads/2016/01/sad-beagle-Wai-Keong-992x561.jpg
AME.14: https://www.the-scientist.com/bio-business/companies-use-crispr-to-improve-crops-65362
AME.15: https://static.producer.com/wp-content/uploads/2020/01/02103022/MJR031010soybean_pods_lit2.jpg
AME.19: https://d279m997dpfwgl.cloudfront.net/wp/2018/03/Untitled-2-1000x680.jpg
AME.24: https://www.hopkinsmedicine.org/sebin/x/s/SecondOp-SickleCells-AndredaLoba-640px.jpg
AME.26: https://geneticliteracyproject.org/wp-content/uploads/2016/09/dn27166-1_800.jpg
AME.27: https://images.agoramedia.com/wte3.0/gcms/infertility-all-treatments-722x406.jpg?width=414
AME.30: https://www.geneticbiocontrol.org/wp-content/uploads/2017/04/GBIRD.jpg
AME.31: https://miro.medium.com/max/3240/1*A-vcJ8euRVOn-MhO7Xcjsw.jpeg
"Innovators & Products" Content:
In.C.1: http://www.crisprtx.com/about-us/mission
In.C.2: http://www.crisprtx.com/programs/hemoglobinopathies
In.C.3: http://www.crisprtx.com/programs/pipeline
In.C.4: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5002234/pdf/nihms-792785.pdf
In.C.5: https://www.editasmedicine.com/
In.C.6: https://www.editasmedicine.com/gene-editing-pipeline/
In.C.7: https://en.wikipedia.org/wiki/Editas_Medicine
In.C.8: https://www.editasmedicine.com/about/
In.C.9: https://cban.ca/gmos/products/ge-animals/enviropig/what-is-enviropig/
In.C.10: https://www.addgene.org/mol-bio-reference/promoters/
In.C.11: https://www.synthego.com/learn/genome-engineering-history
In.C.12: https://aquabounty.com/fast-growing-genetically-engineered-salmon/
In.C.13: https://aquabounty.com/genetically-modified-salmon-to-be-sold-in-the-u-s/
In.C.14: https://oldmooresalmanac.com/genetically-modified-pets-available-now/
In.C.15: https://www.nature.com/scitable/topicpage/recombinant-dna-technology-and-transgenic
In.C.16: https://phys.org/news/2018-05-crispr-edited-rice-major-boost-grain.html
In.C.17: https://www.businesswire.com/news/home/20191122005100/en/Pairwise-Teams-Achieve-Key-Collaboration-Milestones-Early
In.C.18: https://pairwise.com/about-us/
In.C.19: https://fee.org/articles/why-this-new-gene-therapy-drug-costs-21-million/
In.C.21: https://www.mercatus.org/expert_commentary/gmo-labels-wont-make-foods-safer-only-more-expensive
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"Innovators" Media Elements (images, videos, infographics):
In.ME.2: https://static.wixstatic.com/media/5a7fdb_58f70711f7fb4c4abb49ab7ffeebc5c6~mv2.png
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In.ME.5: https://i0.wp.com/post.healthline.com/wp-content/uploads/2019/04/
Couple_Child_Doctor_1296x728-header-1-1296x728.jpg?w=1155&h=1528
In.ME.6: https://www.northside.com/doc/uploads/personalized%20_care%20(1).jpg
In.ME.7: https://www.ttuhsc.edu/medicine/images/feature-program-patient-care-rt.jpg
In.ME.8: https://www.ontariopork.on.ca/Portals/0/EasyDNNNews/844/12801024p3993EDNthumbimg-OntPorkLogo.jpg
In.ME.9: https://ovec.ms/wp-content/uploads/2018/02/Logo-5.jpg
In.ME.10: https://upload.wikimedia.org/wikipedia/en/3/36/AquaBountyTechnologiesLogo.png
In.ME.11: https://vectorlogoseek.com/wp-content/uploads/2018/11/glofish-vector-logo.png
In.ME.12: https://spectrum.ieee.org/image/MzUzNjA3NQ.jpeg
In.ME.13: https://haleykonor.files.wordpress.com/2015/10/pigs-1774.jpg
In.ME.14: https://3dtpnt3tgbjr2opy2x1jh9or-wpengine.netdna-ssl.com/wp-content/uploads/2017/10/Glo-Tetra-1.jpg
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In.ME.22: https://www.businessdestinations.com/wp-content/uploads/2018/08/California.jpg
In.ME.23: https://s3.amazonaws.com/ymca-ynet-prod/files/healthy-family-home/eat-main.jpg
"Issues" Content:
Is.C.1: https://www.genome.gov/about-genomics/policy-issues/Genome-Editing/ethical-concerns
Is.C.2: https://www.avma.org/resources-tools/animal-health-and-welfare/animal-welfare-
Is.C.3: https://www.centerforfoodsafety.org/issues/311/ge-foods/ge-food-and-your-health
Is.C.4: https://www.nature.com/scitable/topicpage/sports-gene-doping-and-wada-764/
Is.C.5: https://wmpeople.wm.edu/asset/index/cvance/glannon
Is.C.6: https://www.microsort.com/requirements/
Is.C.7: https://www.youtube.com/watch?v=_YpACFaK0O4
Is.C.8: https://ghr.nlm.nih.gov/primer/therapy/safety
Is.C.9: https://www.risingtidebio.com/human-gene-therapy-regulations-laws/
Is.C.10: https://www.fooddive.com/news/inside-the-gmo-law-what-needs-to-be-labeled-and-
Is.C.11: https://fas.org/biosecurity/education/dualuse-agriculture/2.-agricultural-biotechnology/us-
Regulation-of-genetically-engineered-crops.html
Is.C.12: https://www.cell.com/molecular-therapy-family/molecular-therapy/fulltext/
Is.C.13: http://sitn.hms.harvard.edu/flash/2015/the-patent-landscape-of-genetically-
Is.C.14: https://www.mayoclinic.org/tests-procedures/gene-therapy/about/pac-20384619
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"Issues" Media Elements (images, videos, infographics):
Is.ME.1: https://happyyouhappyfamily.com/wp-content/uploads/2019/04/banner-bluebonnets-1600x533.jpg
Is.ME.2: https://medicalparkinternational.com/Style%20Library/assets/images/services/Pediatric-Oncology.jpg
Is.ME.3: https://www.thepublicdiscourse.com/wp-content/uploads/2019/03/cross-4062996_1920.jpg
Is.ME.4: https://www.youtube.com/watch?v=OXymaRgMV8A#action=share
Is.ME.5: https://cdn.the-scientist.com/assets/articleNo/66902/aImg/35570/sarepta-l.png
Is.ME.6: https://i.ytimg.com/vi/AVrF5O-vO-A/maxresdefault.jpg
Is.ME.7: https://www.pharmaceutical-technology.com/wp-content/uploads/sites/10/2019/03/flu-vaccine.jpg
Is.ME.8: https://i.bnet.com/blogs/epipen.jpg
Is.ME.10: https://geneticliteracyproject.org/wp-content/uploads/2018/02/doping-2-12-18-2.jpg
Is.ME.12: https://www.youtube.com/watch?v=_YpACFaK0O4
Is.ME.13: https://www.youtube.com/watch?v=A_y8eheuJ8U
Is.ME.14: https://www.snackandbakery.com/ext/resources/images/news/industry_news_2018/FDA-logo_new.jpg
Is.ME.15: https://mediad.publicbroadcasting.net/p/kstx/files/styles/small/public/201305/epa_logo.jpg
Is.ME.16: https://www.medicalcountermeasures.gov/media/37002/nih_320px.jpg?width=320&height=320
Is.ME.18: https://gmoanswers.com/sites/default/files/gmos%20safe.jpg
Is.ME.20: https://consultqd.clevelandclinic.org/wp-content/uploads/sites/2/2019/10/650x450-PEDS-Cancer.jpg
Is.ME.21: https://d24fkeqntp1r7r.cloudfront.net/wp-content/uploads/2018/05/10003308/Scales.jpeg
Is.ME.22: https://www.wada-ama.org/sites/all/themes/custom/wada_theme/images/logos/logo_en2x.png
Is.ME.23: https://upload.wikimedia.org/wikipedia/commons/0/0e/Madre_Naturaleza.jpg
Is.ME.26: https://thehill.com/sites/default/files/styles/article_full/public/blogs/scotus_0.jpg?itok=7y36Py1d
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"Study Resources" Content:
SC.1: https://ghr.nlm.nih.gov/primer/genomicresearch/genomeediting
SC.2: https://www.youtube.com/watch?v=UKbrwPL3wXE
SC.3: https://www.youtube.com/watch?v=2pp17E4E-O8
SC.4: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3547402/pdf/nihms429552.pdf
SC.5: http://www.genetherapynet.com/gene-editing-tools/talen.html
SC.6: https://www.sciencedirect.com/topics/biochemistry-genetics-and-molecular-biology/
SC.7: https://www.ncbi.nlm.nih.gov/pubmed/9804053
SC.8: https://ghr.nlm.nih.gov/primer/therapy/procedures
SC.9: https://www.mayoclinic.org/tests-procedures/bone-marrow-transplant/in-depth/stem-cells/art-20048117
SC.10: http://www.crisprtx.com/programs/in-vivo
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"Study Resources" Media Elements (images, videos, infographics):
SME.1: https://static.wixstatic.com/media/5a7fdb_f5d686d3d80141b5b4d96922357bc8b9~mv2.png
SME.2: https://www.youtube.com/watch?v=UKbrwPL3wXE
SME.3: https://www.youtube.com/watch?v=2pp17E4E-O8
SME.4: https://static.wixstatic.com/media/5a7fdb_f0b72e62e7e948f38c70af30a668b132~mv2.jpg
SME.5: https://www.youtube.com/watch?v=YkVVkzA7QpA
SME.6: https://ghr.nlm.nih.gov/primer/illustrations/adenovirus.jpg
SME.7: http://www.crisprtx.com/programs/in-vivo
SME.8: https://stemcells.nih.gov/sites/all/themes/stemcells_theme/stemcell_includes/4_3.jpg
SME.9: http://www.crisprtx.com/gene-editing/therapeutic-approach